Effects of GH IGF on the Aging Mitochondria of the effects of GHK on pulmonary fibrosis. GHK exerts anti fibrotic Download Scientific Diagram The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin By age 30, your skin produces about 25% less collagen. By 40, that number can reach 40%. This decline affects more than just how your skin looks. It changes how it heals, Before vs. after 3 months of GHK Cu peptide therapy smoother texture, more even tone, and skin that looks healthier overall. Small peptide, big difference